Cost/Benefit of Hepatitis C Treatment: It Does Not End with SVR

treatment of occult hepatitis c virus infection: does it need special attention?

Hepatitis C treatment and SVR: the gap between clinical trials and real-world treatment aspirations.

OBJECTIVE Despite the remarkable improvements in pharmacologic treatment efficacy for hepatitis C (HCV) reported in published clinical trials, published research suggests that, in "real-world" patient care, these medical outcomes may be difficult to achieve. This review was undertaken to summarize recent experience in the treatment of HCV in clinical settings, examining the course of patients t...

Treatment of Occult Hepatitis C Virus Infection: Does It Need Special Attention?

Hepatitis monthly, as an esteemed journal, has published a very important and useful article, a meeting report, about therapeutic aspects of hepatic C virus (HCV) infection (1) in its previous issue. As you know, there is also a new form of chronic HCV infection called occult hepatitis C infection (OCI) that we would like to highlight some important points about it. OCI is defined by the detect...

Treatment of Chronic Hepatitis C in the Aged – Does It Impact Life Expectancy? A Decision Analysis

BACKGROUND AND AIMS Recent studies have demonstrated that the efficacy of interferon-free direct-acting antiviral agents (DAAs) in patients over 70 is similar to that of younger age groups. Evidence continues to mount that life expectancy (LE) increases with successful treatment of hepatitis C (HCV) patients with advanced fibrosis. The evidence in older people is more limited. Our aim was to es...

Steatosis in chronic hepatitis C: why does it really matter?

Hepatic steatosis is a common histological feature of chronic hepatitis C. Various factors are associated with hepatic steatosis, including obesity, high alcohol consumption, diabetes type II, and hyperlipidaemia. These factors may contribute to steatosis in patients with chronic hepatitis C. In humans, hepatitis C virus (HCV) genotype 3 is more commonly associated with steatosis. In vitro stud...